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Syphilis Origin Story: Ancient Bacteria Found in Colombia

Ars Technica - All content •
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Contrary to popular belief, the origins of syphilis may be far older than previously thought. A recent discovery revealed a 5,500-year-old _Treponema pallidum_ genome in Colombia. This finding challenges the traditional narrative that linked the disease's emergence to the 1495 siege of Naples, suggesting a much deeper evolutionary history.

The established origin story placed the spread of syphilis with King Charles VIII's army in Naples. However, the new evidence indicates that pathogens causing treponemal diseases existed millennia before. The French army's actions in Naples created the perfect conditions for the disease to spread. This led to the blaming of different nationalities.

The research suggests a more complex history for this disease. The team was sequencing DNA from an individual in a Colombian rock shelter when the discovery was made. The hunter-gatherer lived 5,500 years ago. This changes our understanding of the disease's timeline and origin points.

This discovery prompts a reevaluation of syphilis's history. It also brings into question the long-held beliefs about its origins. Further research could provide a clearer picture of the disease's early evolution and the factors that led to its global spread. This will help understand the disease's impact.