Our guide to every NFL Week 5 game: Matchup previews, predictions, picks and nuggets

Week 5 of the 2026 NFL season is here, and ESPN has you covered with previews, predictions, picks and nuggets for every matchup. Can the Raiders bounce back against the Patriots after their first loss of the season? Will the undefeated Vikings keep rolling against the Saints? Who has the edge in Bears-Packers, and what can we expect from the 49ers' trip to Seattle?

The Eagles (2-2) head to London to face the Jaguars (3-1) in a 9:30 a.m. ET game on NFL Network. Philadelphia enters with serious offensive problems, ranking 25th in points per game (18.8) and 29th in total yards per game (269.8), with right tackle Lane Johnson retiring and Cam Jurgens traded to Baltimore. Jacksonville, meanwhile, has been converting 51.1% of its third downs, ranked third in the league, and has been especially efficient in third-and-short situations.

Each matchup comes with analysis from NFL Nation reporters, ESPN Research, analytics writer Seth Walder, NFL analyst Ben Solak, fantasy analyst Eric Moody and betting analyst Pamela Maldonado. Football Power Index (FPI) game projections are included, along with final score picks from Maldonado, Moody and Walder for every game.

The week culminates with a Monday Night Football showdown between the Bills and Rams on ESPN. Game times are Sunday unless otherwise noted, and all odds are via DraftKings.

2026赛季NFL第5周来袭，ESPN为您提供每场对决的前瞻、预测、选择和花絮。赛季首败后，突袭者能否在对阵爱国者时重回正轨？不败的维京人能否继续对阵圣徒保持势头？熊队与包装工队的对决谁更占优？49人前往西雅图又会有怎样的表现？

老鹰队（2胜2负）将前往伦敦，于美国东部时间上午9点30分在NFL Network转播中迎战美洲虎队（3胜1负）。费城队目前进攻问题严重，场均得分（18.8分）排名第25位，场均总码数（269.8码）排名第29位，右边锋莱恩·约翰逊宣布退役，卡姆·朱金斯则被交易至巴尔的摩。与此同时，美洲虎队的第三次进攻转换率达到51.1%，位列联盟第三，尤其在第三次进攻距离3码以内时表现高效。

每场对决均配有NFL Nation记者、ESPN研究部、数据分析撰稿人西斯·沃尔德、NFL分析师本·索拉克、fantasy分析师埃里克·穆迪以及博彩分析师帕梅拉·马尔多纳多的分析。赛事包含美式足球实力指数（FPI）的比赛预测，并附有马尔多纳多、穆迪和沃尔德对每场比赛的最终比分预测。

本周的压轴大戏是ESPN转播的周一橄榄球之夜，比尔队对阵公羊队。除非另有说明，比赛时间均为周日，所有赔率数据来源于DraftKings。