Week 5 of the 2026 NFL season is here, and ESPN has you covered with previews, predictions, picks and nuggets for every matchup. Can the Raiders bounce back against the Patriots after their first loss of the season? Will the undefeated Vikings keep rolling against the Saints? Who has the edge in Bears-Packers, and what can we expect from the 49ers' trip to Seattle?
The Eagles (2-2) head to London to face the Jaguars (3-1) in a 9:30 a.m. ET game on NFL Network. Philadelphia enters with serious offensive problems, ranking 25th in points per game (18.8) and 29th in total yards per game (269.8), with right tackle Lane Johnson retiring and Cam Jurgens traded to Baltimore. Jacksonville, meanwhile, has been converting 51.1% of its third downs, ranked third in the league, and has been especially efficient in third-and-short situations.
Each matchup comes with analysis from NFL Nation reporters, ESPN Research, analytics writer Seth Walder, NFL analyst Ben Solak, fantasy analyst Eric Moody and betting analyst Pamela Maldonado. Football Power Index (FPI) game projections are included, along with final score picks from Maldonado, Moody and Walder for every game.
The week culminates with a Monday Night Football showdown between the Bills and Rams on ESPN. Game times are Sunday unless otherwise noted, and all odds are via DraftKings.
Source: ESPN General · Summarized by HeadlinesBriefing