Crunchbase’s weekly roundup spotlights the ten U.S. startups that each secured at least $100 million in fresh capital during the past week. Leading the pack, Sierra raised $950 million, pushing its valuation to $15 billion as investors chase AI‑driven customer‑experience tools. The list also features deals in satellite tech, biotech, and AI infrastructure, underscoring deep liquidity in high‑growth sectors, driving rapid product launches and market expansion.

Space‑focused Astranis closed a $455 million round that combined a $300 million Series E equity tranche with up to $155 million of debt, aimed at scaling high‑orbit satellite constellations. Biotech newcomer Anagram Therapeutics secured $250 million to advance a pill targeting exocrine pancreatic insufficiency, while AI software firm Blitzy attracted $200 million, valuing it at $1.4 billion. These sizable injections fuel expansion and product rollouts, fueling faster R&D and market entry across regions.

Insurance‑tech players also drew strong interest: Corgi Insurance landed $160 million at a $1.3 billion valuation, and Reserv closed a $125 million Series C led by KKR. Renewable‑energy pioneer Panthalassa secured $140 million to develop wave‑powered AI compute at sea. These deals also underscore the strategic importance of AI‑enabled services, signaling investors’ confidence in next‑generation infrastructure.