Pathogenic, a new roguelite twin-stick shooter from developer Aberrant Labs, puts players in the role of a disease invading a human body. The game has quickly gained popularity, selling over 100,000 copies and achieving an "overwhelmingly positive" Steam rating.

Players navigate through various body parts, from skin to the heart, battling immune cells and rival pathogens. Gameplay involves fast-paced twin-stick shooting, dodging bullet-hell projectiles, and strategically collecting upgrades. These upgrades, which can be slotted into the pathogen, allow for extensive build customization and synergistic effects, reminiscent of games like The Binding of Isaac.

Pathogenic rewards experimentation with its modular upgrade system, enabling players to create powerful and unique builds. The game features procedurally generated zones, permanent meta-currency unlocks, and a thematic presentation with scientific-sounding item names and appropriate environmental hazards. Despite its challenge and occasional visual clutter, the game is praised for its engaging gameplay, rewarding progression, and exceptional value at $10.