Aston Villa and Nottingham Forest have been drawn against Lille and Midtjylland respectively in the Europa League last 16, while Crystal Palace will face Cypriot side AEK Larnaca in the Conference League. Villa, seeded and hosting Lille in the second leg, seek to replicate their dramatic 2024 Conference League quarter-final penalty shootout win. Forest, unseeded, travel to Denmark for their tie against Midtjylland, who previously beat them 3-2 in the league phase under Ange Postecoglou.

Palace, also unseeded, host Larnaca in Cyprus aiming for revenge after a 1-0 October league defeat. The draws avoid a repeat of last season's all-English Europa League final, with Villa and Forest potentially meeting in the semis if both progress. Villa face a tougher route, likely encountering Roma or Bologna in the quarters, while Forest could meet Stuttgart or Porto.

The knockout stages run from March 12-19, with the final set for May 20 in Istanbul.