Houston Astros shortstop Jeremy Pena left Saturday night's game against the Seattle Mariners in the fourth inning due to right posterior knee tightness. Pena had singled off starter Luis Castillo and advanced to third base before being replaced by pinch-runner Nick Allen during a pitching change.

Pena, batting .256 with five runs scored this season, has been a key defensive player for the Astros. The 27-year-old shortstop earned World Series MVP honors as a rookie in 2022 and was named American League Championship Series MVP that same year. He made his first All-Star team last season, posting impressive numbers with a .304 batting average, 17 home runs, and 20 stolen bases.

This injury comes at a crucial time for the Astros, who rely heavily on Pena's defensive skills and consistent hitting. The team will need to monitor his condition closely, as his absence could impact their infield stability. Pena's health will be vital for Houston's postseason aspirations, given his proven track record in high-pressure situations.