The Sweet 16 tips off Friday with four intriguing matchups featuring top seeds and surprising underdogs. UConn's 40-0 season continues against North Carolina, while UCLA looks to extend their tournament dominance against Minnesota. The later slate includes Duke's vaunted offense facing LSU's high-powered scorers, and Notre Dame's turnaround story against Vanderbilt's sharpshooting Mikayla Blakes.

Top-seeded UConn enters as heavy favorites against North Carolina, who must improve on their 16 turnovers and 21 offensive rebounds allowed in the last game. UCLA brings Final Four experience to their matchup with Minnesota