Arizona and Michigan enter the Final Four as co-favorites to win the NCAA championship at +175 odds, according to DraftKings. The Wildcats and Wolverines will face off in what appears to be a pick 'em game, with Illinois and UConn as underdogs at +400 and +550 respectively. Duke's +360 odds evaporated after UConn's thrilling last-second upset.

UConn has become a sportsbook liability throughout the tournament, with BetMGM senior trader Michael Ranftle calling them the book's only remaining liability. One New Jersey bettor placed a $300,000 wager on UConn at +205 odds, which would net $615,000. The Huskies have attracted the most bets on FanDuel to win the championship, despite their underdog status.

The betting lines have shifted since opening, with Michigan now favored by 1.5 points over Arizona after initially being slight dogs. Illinois remains favored by 2.5 points over UConn. Sportsbooks would prefer Arizona or Michigan to win the championship, with Circa Sports manager Chase Michaelson calling Illinois a bad result and UConn worse.