Duke is the 2027 NCAA men's basketball championship favorite at +800 odds according to DraftKings, with Michigan second at 12-1. Florida and Arizona, both 2026 1-seeds, follow at 14-1 and 15-1. Bookmakers face significant uncertainty due to the transfer portal and player financial incentives, making early futures markets speculative.

DraftKings director Johnny Avello notes initial odds favor teams with recent competitiveness, but roster details remain incomplete. Michigan's dominant 2026 title run slightly improved their odds from 16-1 to 12-1, while Duke improved marginally from 10-1. Avello highlights Arkansas (18-1) and BYU (30-1) as non-traditional contenders, alongside Illinois and Houston (18-1 each) challenging blue bloods like Kansas (16-1) and Michigan State (16-1).

UConn, despite three recent Final Fours, sits at 20-1 due to regular season inconsistency, surprising Avello as a title contender. Caesars Sportsbook oddsmaker Patrick Berbert calls projecting next season's odds a formidable challenge in the transfer-heavy landscape.