The investigation into Nancy Guthrie's disappearance has hit a roadblock as DNA from a glove found 2 miles from her home shows no matches in the FBI's CODIS database. Authorities confirmed the DNA also doesn't match evidence collected at the property where Savannah Guthrie's mother vanished between January 31 and February 1.

Sheriff Chris Nanos revealed the investigation is shifting focus to the residence itself, where DNA evidence remains under analysis. The sheriff believes whoever took Nancy had a specific target, despite the lack of concrete suspects. Investigators may now turn to Investigative Genetic Genealogy, a technique that helped catch the Golden State Killer in 2018.

The approach differs from standard DNA database searches by using commercially available genealogy sites to identify potential relatives of the unknown suspect. Law enforcement recovered surveillance footage showing a man with his face covered near the property. With no formal suspects identified, the investigation continues while the DNA testing at Nancy's home proceeds.