With GLP-1s threatening billions in sales, packaged-food makers are testing ways to win over the not-so-hungry. Inside an Omaha test kitchen, executives at Conagra recently huddled over plastic trays of microwaved eggs, potatoes and sausage.

One by one, they lifted a package of cheese sauce and poured out the liquid in a slow orange ribbon. Ashley Lind, who heads behavior science at Conagra, studied the breakfast bowl in front of her. She considered: Was it satisfying? No one had tasted the food yet. That was part of the point: Conagra is trying to design products that will entice even people who don't want to eat.

The tasting was one of dozens of tests the maker of Slim Jims and Hungry-Man dinners is conducting with an eye toward the conundrum presented by GLP-1 weight-loss drugs. The medications' power to erase feelings of hunger and satiation threatens to upend the industry's model for growth, where success has often meant selling as much food as possible.