No. 1 Texas faces its next big test at No. 14 Tennessee on Saturday, one of many compelling Week 4 matchups. No. 4 Ole Miss travels to No. 21 Florida, while No. 10 LSU hosts No. 23 Texas A&M in Baton Rouge. No. 18 Michigan welcomes No. 17 Iowa, and No. 20 Oregon visits No. 12 USC.

Here are the lines for all top 25 games, with odds by DraftKings and subject to change. All times Eastern.

Northwestern at No. 5 Indiana (-21): Friday, 8 p.m., FOX. Money line: Northwestern +950, Indiana -1650. O/U 49.5. FPI: Indiana by 18.3 (90%).

No. 1 Texas (-4.5) at No. 14 Tennessee: Saturday, Noon, ABC. Money line: Texas -205, Tennessee +170. O/U 56.5. FPI: Texas by 7.2 (70%).

Illinois at No. 7 Ohio State (-27.5): Saturday, Noon, FOX. Money line: Illinois +1600, Ohio State -4000. O/U 53.5. FPI: Ohio State by 25.6 (95%).

Idaho at No. 11 Texas Tech (-35.5): Saturday, Noon, TNT. O/U 54.5. FPI: Texas Tech by 28.6 (97%).

Wake Forest at No. 16 Louisville (-12.5): Saturday, Noon, ESPN. Money line: Wake Forest +390, Louisville -520. O/U 58.5. FPI: Louisville by 11.9 (80%).

No. 3 Notre Dame (-27.5) at Purdue: Saturday, 2 p.m., Peacock. Money line: Notre Dame -3600, Purdue +1500. O/U 57.5. FPI: Notre Dame by 27.9 (96%).

Oklahoma at No. 2 Georgia (-14): Saturday, 3:30 p.m., ESPN. Money line: Oklahoma +440, Georgia -600. O/U 43.5. FPI: Georgia by 13.8 (83%).

No. 4 Ole Miss at No. 21 Florida (-3): Saturday, 3:30 p.m., ABC. Money line: Ole Miss +136, Florida -162. O/U 60.5. FPI: Florida by 1.1 (53%).

No. 15 Utah (-7.5) at Iowa State: Saturday, 3:30 p.m., FOX. Money line: Utah -360, Iowa State +285. O/U 49.5. FPI: Utah by 9.8 (76%).

No. 17 Iowa at No. 18 Michigan (-5.5): Saturday, 3:30 p.m., CBS. Money line: Iowa +180, Michigan -218. O/U 38.5. FPI: Michigan by 5.3 (65%).

No. 25 Houston (-17.5) at Georgia Southern: Saturday, 4 p.m., ESPN U. Money line: Houston -950, Georgia Southern +625. O/U 54.5. FPI: Houston by 16.9 (88%).