The Premier League midweek fixtures set the stage for a pivotal clash between Newcastle and Tottenham, with Sky Sports' Jones Knows predicting a 1-2 upset. Newcastle's electric form under Eddie Howe, including Joao Pedro's eight fouls in six starts, highlights their ability to disrupt opponents. Meanwhile, Tottenham's struggles continue, with Spurs priced at 10/1 for relegation and just one home win in 11 matches. The expert emphasizes Newcastle's tactical frustration leveraging fan discontent, making the half-time/full-time market (5/2) a key betting angle.

Elsewhere, Chelsea vs. Leeds sees Garner (11/4 for +2 fouls) and Scott (14 fouls in eight games) as central midfield battlegrounds. Everton's James Garner and Bournemouth's Alex Scott could dictate the tempo, with Garner's 10/4 odds reflecting his consistency. West Ham's Crysensio Summerville (9 shots on target in six games) and Manchester United's vulnerabilities make their 2-2 prediction a high-scoring affair. Brighton's crisis deepens with one win in 12 games, facing Villa's ruthless home record (10/11 for maximum points).

Crystal Palace's Jorgen Strand Larsen (19/2 for a card) and Burnley's physicality loom large, while Nottingham Forest's combative Gibbs-White (10/1 for goal+card) adds drama. Sunderland vs. Liverpool sees Van Dijk facing Bobbey's aggressive style, with Sky Bet's foul markets reflecting role-specific matchups. Each fixture carries implications for midtable survival and European contention.

Quick Fact: Spurs are 10/1 to be relegated according to Sky Bet odds.