Week 6 of the NFL kicks off Thursday night as the Seattle Seahawks visit the Denver Broncos on "Thursday Night Football." The defending champions are early 3-point favorites, one of seven games with a spread of three points or less this week. Sunday's action begins with an AFC South clash between the Houston Texans and Jacksonville Jaguars in London, with a 9:30 a.m. ET start.
The Los Angeles Rams are the biggest favorite of the week, laying 12.5 points at home against the Arizona Cardinals. The total for that game is 52.5, one of four games with a total over 50. The Rams are rated at an 86% probability to win the game outright, according to ESPN's FPI.
The Dallas Cowboys, coming off a loss to the previously winless Tampa Bay Buccaneers, head to Lambeau Field to face the Green Bay Packers on Sunday night. The San Francisco 49ers host the Washington Commanders on "Monday Night Football" at 8:15 p.m. ET on ESPN/ABC to close out the week.
The Cincinnati Bengals, Detroit Lions, Miami Dolphins and Minnesota Vikings are on bye. Odds are from DraftKings and are subject to change. All times are Eastern.
Source: ESPN NFL · Summarized by HeadlinesBriefing