Jacob Misiorowski delivered a historic performance, matching his career high with 12 strikeouts and throwing 57 pitches of at least 100 mph. The Brewers' right-hander carried a no-hitter into the sixth inning, allowing just one run on two hits and one walk in seven innings. His top velocity reached 103.4 mph, improving his ERA to 1.83 as Milwaukee extended their NL Central lead over St. Louis to 2½ games.

Christian Yelich provided early support with a two-run homer in the first inning, helping the Brewers build a 3-0 lead off Matthew Liberatore. Andrew Vaughn went 3-for-4 while Milwaukee added single runs in the sixth and eighth innings. Liberatore countered with 10 strikeouts in five innings, but the Brewers' pitching and timely hitting proved decisive in the 5-1 victory.

Misiorowski's 100-mph pitches broke the previous record of 47 set by Hunter Greene in 2022. His performance ended the Cardinals' scoring streak against him at 29⅓ innings, though he fell short of Teddy Higuera's Brewers record of 32 straight scoreless innings in 1987. The solid victory gives Milwaukee a commanding lead in the division race with the Cardinals trailing by 2½ games.