Offensive line continuity and efficiency are driving fantasy value for several backfields heading into 2026. The Denver Broncos return all five starters, creating a high floor for J.K. Dobbins, who averaged 5.1 yards per carry last season. Similarly, James Cook III remains a top target for Buffalo after leading the league with 1,621 rushing yards behind a unit that led the league in run block win rate.

Philadelphia offers a bounce-back opportunity for Saquon Barkley. After his production dipped to 1,413 yards and nine scores in 2025, a healthier line and Sean Mannion's offense should restore his elite ceiling. Meanwhile, Kyren Williams remains a priority for the Rams, who ranked second in run block win rate last year despite the retirement of Rob Havenstein.

Conversely, poor line projections make Tennessee and Cleveland risky bets. Tony Pollard faces a struggle in Tennessee with a unit likely to remain near the league bottom. In Cleveland, Quinshon Judkins faces efficiency risks due to a complete line rebuild and a shaky quarterback situation involving Deshaun Watson, who is recovering from multiple Achilles tears. These factors cap the ceiling for backs in these systems regardless of their individual talent.