Duke, Arizona, Michigan and Florida secured the top four seeds in the men's NCAA tournament, with one-loss Miami (Ohio) earning an at-large bid as the final 11-seed. Duke, the Blue Devils, claimed the overall top seed, bolstered by an 11-game winning streak and player of the year contender Cameron Boozer. Arizona leads the West, Michigan the Midwest, and Florida the South, while the East Region features UConn as the 2-seed. The selection committee's decision to drop Michigan from the No. 2 overall seed to No. 3 followed their Big Ten final loss to Purdue moments before bracket announcements. Miami (Ohio), despite a 31-1 record, barely secured the final spot as an 11-seed, facing a First Four game against SMU in Dayton. Injuries significantly impacted rankings, notably dropping North Carolina to a No. 6 seed after losing Caleb Wilson to a broken thumb and Texas Tech to JT Toppin's season-ending knee injury.