Week 2 of the 2026 NFL season features 15 games with key division matchups including Vikings at Bears, Panthers vs. Falcons, Raiders vs. Chargers, and Seahawks vs. Cardinals. A highlighted quarterback duel is Trevor Lawrence (Jaguars) vs. Bo Nix (Broncos). ESPN's NFL Nation reporters provide locker room insights, while Seth Walder offers analytics predictions, Ben Solak gives watchability ratings, Eric Moody shares fantasy intel, and Pamela Maldonado delivers betting analysis.

The article includes FPI projections and final score picks from Maldonado, Moody, and Walder for every game. The slate concludes with Monday Night Football: Giants vs. Rams on ESPN. Game times are Sunday unless noted, with odds via Draft Kings.

Matchups covered: MIN-CHI, CIN-HOU, NO-BAL, PIT-NE, GB-NYJ, PHI-TEN, CAR-ATL, CLE-TB, JAX-DEN, LV-LAC, WSH-DAL, SEA-ARI, MIA-SF, IND-KC, NYG-LAR. Notable stats: Vikings DC Brian Flores posted a 71.7% blitz rate in Week 1, nearly tripling the NFL average. Bears coach Ben Johnson noted Flores' unpredictability, saying 'there always is' something new with him.