New World screwworm larvae were intercepted at a Florida USDA quarantine facility on an imported horse from Argentina, marking the first U.S. detection since eradication efforts in the 1960s. Officials confirmed no spread beyond the facility, but the incident highlights vulnerabilities as Central American outbreaks surge. $1.1 billion in USDA funding aims to sterilize flies and block imports, yet Ohio remains unscathed after a 2025 Maryland human case linked to El Salvador travel. Screwworm infestations cause severe tissue damage in livestock and humans, with symptoms including maggot-filled wounds and necrotic tissue. USDA's strategy combines sterile insect releases and border surveillance, but experts warn climate shifts could accelerate northern migration.