A catastrophic multi-vehicle crash on Interstate 25 south of Pueblo has killed four people and hospitalized 29 others, involving over 30 vehicles including six semi-trucks. The Colorado State Patrol reported the pileup occurred around 9:58 a.m. on Feb. 17, with both directions of the interstate closed between mileposts 93 and 94.

The crash investigation suggests dust storms and high winds created near-zero visibility conditions, contributing to the chain-reaction collision. First responders from multiple agencies are working the scene, with the Pueblo County Coroner's Office set to release victim identities after notifying next of kin. The Vehicular Crimes Unit is leading the investigation.

Transportation officials warn the interstate could remain closed for an extended period as crews clear wreckage and conduct their investigation. The Colorado Department of Transportation advises drivers to treat dust storm conditions like blizzard conditions - turn on lights, reduce speed, and proceed with extreme caution. Travelers are urged to check COtrip.org for real-time updates and consider alternate routes until conditions improve.