The Wall Street Journal's April 4, 2026 news quiz covers major business and political developments. Alexander Vindman, the former Trump whistleblower, is running for a Senate seat, while Eli Lilly received FDA approval for its new once-a-day weight-loss pill, joining competitors in the lucrative obesity drug market. NASA launched four astronauts aboard its Crew Dragon capsule for a lunar fly-around mission.

Economic news includes three potential mega-IPOs on the horizon, though one major listing is unlikely this year. Anthropic scrambled to contain fallout after accidentally exposing code for its competitive AI agent. Venezuela's first lady Cilia Flores faces allegations of running a criminal enterprise, while President Trump unveiled mock-up images of his planned presidential library tower.

Corporate news features Nestlé's creative handling of a massive KitKat heist, though the exact number of stolen bars remains unspecified. The quiz also touches on tax policy changes, with one state implementing a millionaire income tax starting in 2028 despite currently having no income tax. These questions span healthcare innovation, space exploration, political developments, and corporate strategy.