Sep 28, 2026, 11:00 AM ET — One game remains in Week 3, but odds for Week 4 of the NFL season are out. The Cleveland Browns host the Pittsburgh Steelers on Thursday night to open the action. The Steelers are a 2.5-point favorite in a game with the lowest total of the week (38.5).

The week is full of tight spreads, with 11 games having spreads of four points or less. The Baltimore Ravens (-11.5) hosting the Tennessee Titans and the Miami Dolphins visiting the Minnesota Vikings (-10) are the major outliers. The Jacksonville Jaguars-Cincinnati Bengals matchup has the highest total at 51.5.

Week 4 wraps up with an NFC South battle between the New Orleans Saints (-2.5) and Atlanta Falcons on "Monday Night Football" (8:15 p.m. on ESPN). Odds by Draft Kings and subject to change. FPI favorites include the Bears by 4.5 (66% win probability) and the Ravens by 10.1 (83%).