Jaxson Dart threw two touchdown passes to Isaiah Likely as the New York Giants beat the Dallas Cowboys 28-20 on Sunday night in John Harbaugh's coaching debut. Dart completed 23 of 29 passes for 230 yards and added 54 rushing yards. Malik Nabers returned from ACL injury with six catches for 69 yards, while Cam Skattebo rushed for one touchdown after recovering from leg and ankle injuries.

The Giants opened their season with a statement victory over the Cowboys, who committed eight penalties for 85 yards. In a pre-game ceremony honoring 9/11 victims, Harbaugh wore an NYPD hat in the first half and an FDNY cap in the second. The victory marked a strong start to Harbaugh's tenure following his move from Baltimore.