With the latest Premier League fixtures kicking off Tuesday night, BBC Sport provides comprehensive injury updates and Fantasy Premier League insights across all matches. Chelsea host Leeds United in the early kickoff, with Reece James facing a late fitness test after recovering from a minor injury but now battling a virus. Leeds United will miss Pascal Struijk due to a hip problem, while Dominic Calvert-Lewin remains a doubt after recent illness.

Chelsea's Cole Palmer (£10.5m) enters the fixture in excellent form after his hat-trick against Wolverhampton Wanderers, making him the fifth most-bought FPL midfielder this week. Meanwhile, Everton face Bournemouth with Jack Grealish sidelined by a stress fracture, though Jarrad Branthwaite could make his first start since returning from a serious hamstring injury. Tottenham Hotspur travel to Newcastle United without several key players including Destiny Udogie (hamstring) and Cristian Romero (suspended), while West Ham United host Manchester United with Jean-Clair Todibo the only confirmed absentee.

Aston Villa welcome Brighton & Hove Albion Wednesday, with James Milner potentially equaling the all-time Premier League appearance record of 653. Manchester City face Fulham with manager Pep Guardiola set to provide squad fitness updates. The comprehensive coverage includes key FPL statistics, such as Crysencio Summerville's five consecutive goals for West Ham and Bruno Fernandes' consistent returns for Manchester United.