US stock-index futures fell Thursday as hopes for a US-Iran deal faded amid escalating Middle East tensions. The looming Trump administration deadline for negotiations has investors on edge, with market sentiment souring as diplomatic efforts appear to stall. Oil prices climbed higher, reflecting growing concerns about potential supply disruptions in the region.

Traders are increasingly worried about the economic fallout from a potential military confrontation between the US and Iran. The Middle East conflict has historically triggered market volatility, with energy markets particularly sensitive to regional instability. Wall Street's early reaction suggests investors are bracing for continued uncertainty as the deadline approaches.

The sell-off in futures markets indicates growing anxiety about the geopolitical situation's impact on global trade and economic growth. With oil prices already elevated, any further escalation could compound inflationary pressures and force central banks to reconsider monetary policy stances. The market's negative reaction underscores how quickly investor sentiment can shift when geopolitical risks intensify.