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NFL Week 5 Predictions: Upsets, Sleepers & TD Scorers

ESPN NFL •
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Week 5 of the 2026 NFL season is underway after the Buccaneers defeated the Cowboys on Thursday night. Fifteen NFL experts offer their biggest predictions for Sunday and Monday action.

Betting analyst Pamela Maldonado identifies two potential upsets. The Las Vegas Raiders (+3.5, +164 moneyline) face the New England Patriots, where QB Kirk Cousins can exploit New England's weakness against play-action. The New York Giants (+3.5, +150 moneyline) travel to Washington, where QB Jameis Winston can target WR Malik Nabers against a vulnerable Commanders pass defense.

Analytics writer Seth Walder projects stat lines for three players, including Steelers RB Jaylen Warren, projected for 16 carries, 104 yards, 1 touchdown and 1 reception for 19 yards.

Fantasy writer Eric Moody suggests three sleepers, while analyst Matt Bowen predicts three players who will find the end zone. National analyst Ben Solak rounds out the predictions with four wild-card picks.

Key questions heading into the weekend: Can the Giants pull off an upset? Will Jaylen Warren continue his heavy workload? Is Cardinals QB Jacoby Brissett a safe fantasy starter? Which Bears receiver will score?

Source: ESPN NFL · Summarized by HeadlinesBriefing