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NFL Week 4 Predictions: Upsets, Sleepers & Stat Lines

ESPN NFL •
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Week 4 of the 2026 NFL season is underway after the Browns edged the Steelers 27-24 on Thursday night. Our NFL experts offer 15 predictions for the remaining games, covering upsets, fantasy sleepers, projected stat lines and TD scorers.

Betting analyst Pamela Maldonado predicts three upsets, including the Denver Broncos (+3, +124 moneyline) at the San Francisco 49ers. With Nick Bosa out, the 49ers may struggle to pressure Broncos QB Bo Nix, whose defense has held top QBs under 60% completion rate.

Analytics writer Seth Walder projects stat lines for three players, while fantasy writer Eric Moody suggests three sleepers. Meanwhile, Matt Bowen predicts three players who will find the end zone.

Other key predictions include the Atlanta Falcons (+2.5, +124) at the New Orleans Saints, where Bijan Robinson has a clear advantage, and the Dallas Cowboys (+3, +136) at the Houston Texans. Analyst Ben Solak adds three wild-card predictions, including potential impacts from Bears coach Ben Johnson.

Source: ESPN NFL · Summarized by HeadlinesBriefing