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NFL Inactives: Nico Collins out, Darnold uncertain

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Michael F. Florio Sep 24, 2026, 12:52 PM ET Close Michael F. Florio is a fantasy football writer and analyst for ESPN Fantasy.

He is an analyst on NFL Network's NFL Fantasy Live and frequent guest on other network shows. He has been a fantasy football analyst for the last 15 years, with his work featured at a number of publications, and is an FSWA award winner. Whom should you start? Whom should you sit? To help you set your fantasy football lineups and avoid starting an offensive player who won't be in the lineup, we'll post fantasy-relevant updates and analysis here as NFL teams release their official inactives lists.

Official Sunday inactives should begin coming in approximately 90 minutes before the scheduled kickoff times: around 11:30 a.m. ET for the early games and 2:30 p.m. ET for the late-afternoon games. Refresh often for the latest information. Don't forget to check these out: Mike Clay's Playbook | Week 3 Buzz Week 3 Rankings | Matchup rankings for Week 3 Biggest concerns heading into Week 3.

Players with early starts DJ Moore, WR, Bills (shoulder): Moore was limited Wednesday and wearing a noncontact jersey. He then missed practice Thursday before logging another limited session with the noncontact jersey Friday. He is questionable heading into Week 3 -- and truly could go in either direction, although it's worth noting that Moore has not missed a game since 2020.

If he's active, fantasy managers should plan to start him, even if he is somewhat limited. If he sits, expect Khalil Shakir to see more work. Keon Coleman, WR, Bills (ankle): Coleman also missed practice this week.

He was able to log a limited session Friday and is also questionable heading into Sunday. If Coleman sits, Joshua Palmer and Skyler Bell will be the next options. The main target for Buffalo would be Dalton Kincaid.

Some potential outside replacement options for any missing Bills are Devaughn Vele, Denzel Boston, Josh Downs, Adonai Mitchell*, and Dontayvion Wicks. *See below. Jalen Coker, WR, Panthers (ankle): After missing practice Thursday, Coker returned in a limited fashion Friday -- his second practice of the week. He is questionable for Week 3.

It's worth noting that Coker missed practice last week and still ended up suiting up (and performing adequately for fantasy managers). He has seen nine targets in both games this season.