The NFL combine kicks off in Indianapolis, offering scouts their first look at top prospects for the 2026 draft. ESPN's fantasy football experts have identified 12 key players who could make waves in the evaluation process. These athletes represent various positions and backgrounds, each bringing unique skills that could translate to immediate fantasy relevance.

Among the quarterbacks, Fernando Mendoza stands out as a Cinderella story. The Indiana star went from 72nd-ranked QB in his high school class to Heisman Trophy winner in just four years. Despite skipping on-field drills at the combine, his accuracy and processing speed make him a potential first-round pick. Ty Simpson from Alabama presents a more complex evaluation, with impressive moments offset by late-season struggles. His decision to participate in all combine drills could help teams assess his upside.

In the running back category, Jeremiyah Love and Jadarian Price headline Notre Dame's impressive duo. Love, the Doak Walker Award winner, brings explosive speed and receiving skills that could make him a Day 1 fantasy contributor. Price, recovering from an Achilles tear, aims to prove his durability while showcasing pass-catching abilities. Jonah Coleman from Washington rounds out the group with his physical running style and potential as a three-down back.