Week 6 of the 2026 NFL season is here, and the slate is packed with compelling matchups. Will the Chiefs stay unbeaten, or can the Chargers finally notch their first win? Could the Raiders get back on track against the feisty Bills? Divisional showdowns like Texans-Jaguars and Ravens-Browns headline the action, and the Cowboys-Packers Sunday night game promises plenty of intrigue.
NFL Nation reporters share the best thing they heard this week from inside the locker rooms, and ESPN Research highlights a key stat to know. Analytics writer Seth Walder offers a bold prediction for each matchup, while fantasy analyst Eric Moody shares fantasy football intel and betting analyst Pamela Maldonado provides insights for each contest.
The Texans (1-4) visit the Jaguars (4-1) in London, with Jacksonville favored by 2.5 points. Houston expects new wide receiver Marvin Harrison Jr. to play, and he and C.J. Stroud could recreate their Ohio State magic from 2021-22. Jacksonville's Trevor Lawrence has struggled against Houston, throwing more interceptions (11) than touchdowns (eight) against them, though he currently leads the NFL with an 8.8% off-target percentage.
The Jaguars have also allowed 608 passing yards on throws of 15-plus yards downfield this season, second most in the league behind the Lions. The Monday Night Football matchup between the Commanders and 49ers closes out the week on ESPN.
Source: ESPN NFL · Summarized by HeadlinesBriefing