Duke asserted control over Siena with a commanding 43-32 halftime lead. The Blue Devils' 80.7% win probability held true as they dictated game tempo. Siena struggled from three-point range, shooting just 39% while Duke connected at 55%. The halftime score reflected Duke's defensive prowess and offensive execution throughout the opening half.

Game statistics highlighted Duke's complete performance. They limited Siena to a 39% field goal percentage while shooting 55% themselves. The Blue Devils dominated the free throw line, making 100% of their attempts. Key players like Maliq Brown secured crucial defensive rebounds that extended Duke's lead and maintained their control of the game's momentum.

Siena's shooting struggles proved decisive, particularly from beyond the arc. Brendan Coyle and Nikolas Khamenia both missed long three-point attempts that could have shifted momentum. Gavin Doty's defensive rebound preserved possession for Duke during critical moments. Duke's comprehensive performance solidified their position in the competitive 2025-26 conference standings.