Apple TV is adding another high-profile comedy to its lineup with Brothers, premiering Wednesday, September 23 with two episodes followed by weekly releases through November 4. The series stars Matthew McConaughey and Woody Harrelson as fictionalized versions of themselves, whose friendship is thrown into chaos when they uncover a decades-old secret: they might actually be brothers.

The showrunner is Lee Eisenberg, who was a significant creative player on The Office, serving as writer and producer for seasons 2 through 6. In Brothers, after Woody's daughter's engagement falls apart, he heads to Austin for an extended stay at Matthew's ranch. What begins as a healing getaway quickly spirals when Matthew's mother, Ma Mac (played by Holland Taylor), accidentally reveals a long-buried secret.

As Woody turns the ranch upside down in pursuit of the truth, Matthew faces his own identity crisis: a potential run for governor of Texas. The result is a heartfelt, chaotic story about friendship, family, fame and the messy line between myth and reality.

Also coming to Apple TV in September alongside Brothers: a new season of Slow Horses, an original crime thriller called Last Seen, and the Ryan Reynolds film Mayday.