Health Secretary Robert F. Kennedy Jr. faces fierce industry opposition to his plan to eliminate the GRAS loophole that allows food companies to self-determine ingredient safety. Companies are warning of lawsuits before an official proposal has been unveiled, with lawyers claiming such requirements would exceed FDA authority and face legal challenges.

The GRAS system has enabled thousands of ingredients to enter the U.S. food supply without government review, dating back to 1958 when it was meant for common substances like vinegar. Trade groups argue mandatory notifications would create significant administrative burdens, slow innovation, and disproportionately affect small and mid-sized firms that lack resources for complex regulatory submissions.

Kennedy's team has garnered widespread support for food reform despite the resistance. The proposal awaits White House clearance before publication as a proposed rule, with industry already alerting officials about potential legal challenges and practical concerns regarding the FDA's capacity to review an influx of new ingredient notifications.