US stock futures tumbled as military conflict erupted in Iran, sending the S&P 500 Index futures down 1.2% by 7:45 a.m. New York time. The sudden escalation rattled global markets, triggering a broad sell-off across major indices. Investors fled to safe-haven assets amid mounting geopolitical uncertainty.

Key premarket movers reflected the market turmoil, with shares of AES, Amazon, American Air, Exxon, and UniQure all under pressure. The conflict's impact rippled through multiple sectors, hitting energy stocks particularly hard as oil prices spiked on supply disruption fears. Technology and airline stocks also faced significant declines.

Market volatility is expected to remain elevated as traders assess the conflict's potential economic fallout. The Federal Reserve's monetary policy path could face renewed scrutiny if geopolitical tensions persist. Investors will closely monitor developments throughout the trading day for signs of escalation or de-escalation that could further sway market sentiment.