Steve Borthwick is set to implement sweeping changes to England's backline for their Six Nations match against Italy. Multiple injuries and positional moves mean not one backline position will feature the same player as in the defeat to Ireland. Fin Smith looks likely to start at fly-half, with Seb Atkinson poised to take the inside center role.

Ollie Lawrence's knee injury forces Tommy Freeman to move from wing to midfield, allowing Tom Roebuck to return to the starting lineup. Cadan Murley will likely start on the other wing, while Marcus Smith and Elliot Daly compete to replace Freddie Steward at full-back. Ben Spencer is expected to start at scrum-half with Alex Mitchell injured.

Veteran England centurion Danny Care believes Elliot Daly's experience could prove valuable, particularly his "big left boot" and aerial ability. Daly's 74 caps and three British and Irish Lions tours bring crucial know-how for the pressure-cooker environment in Rome. England faces a daunting rebuild after their 42-21 loss to Ireland.