Fantasy Premier League managers face a major Manchester derby decision this weekend. The latest FPL team of the week is loaded with Manchester City and Liverpool attackers. Antoine Semenyo earns an immediate spot after scoring in his first two games for City. The team is built on a £100m budget, focusing on current form and favorable fixtures ahead of Saturday's crucial match at Old Trafford.

The defensive picks are built for clean sheets. Robin Roefs of Sunderland is a top choice against a goal-shy Crystal Palace, while Micky van de Ven gets the nod for Tottenham against struggling West Ham. In midfield, Florian Wirtz and Bruno Guimaraes are in red-hot form. Wirtz is a key Liverpool asset facing Burnley's poor away defense, and Guimaraes has posted three straight double-digit returns.

Up front, Erling Haaland is the obvious captain pick against a Manchester United defense that has failed to keep a clean sheet all season. He's joined by Hugo Ekitike, another dangerous Liverpool striker facing Burnley. Dominic Calvert-Lewin of Leeds also makes the cut, having scored nine goals this season. This selection leans heavily on attacking assets from top clubs with favorable matchups.