The Amen break is a seven-second drum break from the 1969 track "Amen, Brother" by the American soul group the Winstons, released as the B-side of "Color Him Father". Performed by Gregory Coleman, the break comes at about 1:26 into the song and features a delayed snare hit and syncopated pattern.

With the rise of hip-hop in the 1980s, the break was sampled in hits like "Straight Outta Compton" by N.W.A and "Keep It Going Now" by Rob Base & DJ E-Z Rock. In the 1990s it became a staple of drum and bass and jungle music, used in thousands of tracks across genres, making it one of the most sampled recordings in history.

The Winstons received no royalties. Bandleader Richard Lewis Spencer was unaware of its use until 1996, after the statute of limitations had passed. He initially condemned it as plagiarism but later found it flattering. Coleman died homeless and destitute in 2006, unlikely aware of his impact.

In 2015 a GoFundMe campaign raised over £18,000 for Spencer, who died in 2020. In 2026, "Amen, Brother" was selected by the US Library of Congress for preservation in the National Recording Registry for its cultural, historical, and aesthetic importance.